Using Marijuana for Parkinson’s Disease (Science Explained)


Parkinson’s Disease (PD) is the second most common neurodegenerative disorder related to age, just after Alzheimer’s disease.

The stats are alarming — between 7 and 10 million people around the world live with this disease.

In fact, every year, about 6,600 people in Canada are diagnosed with the PD, meaning that it affects one in every 500 Canadians.

PD is a degenerative disease and usually gets worse over time. There’s still little known about its exact cause, and unfortunately, medicine does not have a definite cure for it right now.

However, it seems that marijuana and Parkinson’s share a connection we were not initially aware of, until just recently.

The synergy of cannabinoids and PD caught the eye of scientists and academic research, proving once again that there’s a reason why cannabis is so powerful:

Cannabis is useful in relieving Parkinson’s symptoms because cannabinoids modulate CB receptors (which improve motor and nonmotor symptoms) and protect dopaminergic neurons (which provides neuroprotection and a dopamine boost).

But that’s just the tip of the iceberg.

What is Parkinson’s Disease?

Parkinson’s Disease (PD) is a degenerative disorder of the nervous system, mostly affecting motor skills.

It all starts with slightly shaky hands, and as the condition develops, patients affected by the disease have more and more difficulties to control their movements. Their motor skills become slower, more rigid and they develop walking difficulties.

Furthermore, there are “nonmotor” symptoms such as emotional and sensory problems, as well as sleep disorders. A number of patients will develop depression and dementia, too.

What is typical for this disease is that men are affected more than women.

Parkinson’s mostly affects people over 60, but it can even happen before the age of 50 which is known as young-onset Parkinson’s disease. Once diagnosed, the life expectancy is between 7 and 15 years.

Unfortunately, we still don’t know a great deal about PD. What do we know so far is that abnormal aggregates of proteins develop in nervous cells, causing the death of neurons. Also, PD patients don’t produce enough dopamine in their system, and all of this is causing involuntary writhing movements.

Parkinson’s is dominantly genetic, meaning that probably other members of patient’s family will develop the disease. As much as 15% of patients have a first-degree relative with the disease.

However, research has also found that environmental factors may cause PD. Head injuries (such as concussions), smoking and drinking coffee have all been linked to developing the disease.

As I’ve said, there is no definitive cure, but there are some types of therapies that can help reduce the symptoms and improve overall life quality of patients.

For severe cases, a deep brain stimulation surgery can be performed by placing microelectrodes to stimulate the brain and reduce the symptoms affecting patient’s motor skills.

However,  typical treatment for Parkinson’s includes medications. The downside to PD pharmaceuticals are the well known side effects, plus the fact that they can become less effective over time.

So, is there a natural alternative to PD medications? What about cannabis?

Research on cannabis and Parkinson’s disease

Back in 2004, 339 Parkinson’s patients attending Prague Movement Disorder Centre took an anonymous questionnaire about the subjective improvement in their motor symptoms after taking cannabis.

Of those who had used cannabis, 45.9% said they noticed an improvement in some way. In fact, about 30% of patients who used marijuana said they noticed less tremors and 44.7% noticed an improvement in the slowness of movement.

In one small study conducted at the Tel Aviv University in Israel, 47 PD patients were observed. During a period of few months, participants used medical marijuana and 82% reported improvement in their symptoms like stiffness and tremor.

They also noticed an improvement in non-motor symptoms such as pain, mood and sleep.

Furthermore, in a similar study, patients noticed an improvement in symptoms just 30 minutes after taking cannabis.

Indica or Sativa for Parkinson’s disease?

Long story short, while Sativa is like having a cup of coffee, Indica is more like having a nice relaxing cup of herbal tea.

Cannabis Sativa is one of two types of marijuana plants. Sativa strains are usually recommended for daytime use because of their energizing properties, but they also have strong cerebral effects.

On the other hand, Cannabis indica produces sedative effects which makes it favorite among people with sleeping problems.

These strains are usually more potent than sativas, making people feel relaxed, sleepy and very hungry. Indica strains are usually recommended for nighttime use.

But, when it comes to Parkinson’s Disease, the first recommendation would be Indica because of is relaxing and painkilling properties, and since it helps with sleeping disorders.

There are also a few Sativa strains which could be a good fit for your needs, as well as hybrids (the mixture of both Indica and Sativa).

10 best strains for Parkinson’s disease

Finding the right strain for your specific needs can be a challenge. We are all unique and certain strains can have different effects on people.

That’s why it’s super important to be patient and do some research before signing up to an LP or visiting a dispensary.

Here are a few strains to help you start your journey on finding the right one.

Kobain Kush

Named after the famous rock-star, Kobain Kush is a perfect Indica for PD patients since it’s well balanced and doesn’t induce sleepiness. Very effective in reducing pain and stress, its relaxing effect makes patients forget their worries while calming both body and mind. What PD patients can benefit the most from this strain is that it’s great for muscle spasms and tremors.


Great for daytime use, this Indica strain does not produce the couch-lock effect nor sedation. For Parkinson’s patients who wish to avoid intense psychoactive effects, Harmonia front-loads CBD behind a slightly decreased THC profile. This harmonious balance (hence the name) stands a good chance of blocking the protein production associated with nerve cell damage in PD.


Although its name sounds like hell, Trainwreck actually has stimulating and soothing effects on our whole system. This one is potent in the THC department but its calming effect helps get rid of tremors and improve the balance.

Critical Cheese

A few hits of Critical Cheese provides a very fast uplifting effect. This is one of the first strains to be recommended to PD patients because of its high CBD levels.

This potent, but one of the most relaxing Indica strains, is best known for its calming qualities. It relaxes, relieves pain and reduces stress away. It increases the dopamine levels which is associated with PD.

Amnesia Haze

Amnesia Haze is a Sativa strain usually recommended for daytime use since it provides a boost of energy. It also awakens creativity in us and helps find some relief from stress. Amnesia Haze is effective in combating depression, fatigue and pain too.


From the experience of chronic pain patient’s, Hashberry does not seem to work on severe pain, but it is more effective in low to moderate pain. It has strong sedative effects so it’s best to use it in the afternoon and evening chill. It’s great for beating insomnia, too, as well as depression, anxiety and everyday stress.

Blue Diesel

Preferred for daytime use since it has no couch-lock and numbing effects. Instead, the effect of Blue Diesel is slow, smooth and long-lasting. It contains high levels of CBD, too, which makes it welcome for Parkinson’s.

Lavender Haze

This Indica dominant hybrid is a very potent strain, best recommended for after-work use. Beginners report being very sleepy after using Lavender Haze, while more experienced consumers feel more energized. It’s been used for different medical conditions such as insomnia and depression, including PD, too. Just take it easy with this strain, as it can cause a slight paranoia.

Cherry Kola

Very high in THC (up to 21%) and very low in CBD, which makes it perfect for conditions such as stress, anxiety and pain. Since it has a strong sedative effect, it’s recommended for nighttime use, for deep relaxing feeling and peaceful sleep.

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