Cannabinoids can prevent the long-term negative consequences of exposure to severe stress, according to a new study published by the journal Hippocampus, and e-published ahead of print by the U.S. National Institute of Health.
“Exposure to excessive or uncontrolled stress is a major factor associated with various diseases including post-traumatic stress disorder (PTSD)”, begins the study’s abstract. “The consequences of exposure to trauma are affected not only by aspects of the event itself, but also by the frequency and severity of trauma reminders.”
According to researchers; “Several lines of evidence support the role of the endocannabinoid (eCB) system as a modulator of the stress response. In this study we aimed to examine cannabinoids modulation of the long-term effects (i.e., 1 month) of exposure to a traumatic event on memory and plasticity in the hippocampus and amygdala.”