Is CBG The New CBD?


There are more than 100 cannabinoids in the cannabis plant. Besides THC, they all are found in fairly small percentages, but still have benefits in both medical and recreational realms. CBG is one such cannabinoid ready to take the world by storm.


CBG or cannabigerol is non-psychoactive, so it won’t get you high. But its importance goes far beyond the concerns of psychoactivity. As researchers discover more about cannabinoids and other constituents within the cannabis plant, CBG is revealing itself as a potentially therapeutic compound. This cannabinoid won’t be chosen for its movie-enhancement capabilities or couchlock; it will most likely be used for medical purposes.


Cannabigerol (CBG) comes from CBGA, the acid precursor of the cannabinoid. With the help of natural enzymes in the plant, CBGA will morph into other acidic cannabinoids. These are CBDA, THCA, and CBCA. These are the cannabinoids that are converted into the famous CBD and THC when decarboxylated (heated up).

This information can help us understand why we haven’t heard much about CBG nor found strains with high contents of it. Because CBGA turns into other cannabinoids, the more THC and CBD a grower wants, the less CBG there will be in the plant. Most strains will have less than 1%, going as low as 0.1% of this cannabinoid. But this trend has already started to change. Maybe in the future, we’ll be seeing strains with high CBG contents. Growers are already working on genetic manipulation and cross breeding to achieve this.

Extraction is also a booming sector of the cannabusiness as it allows scientists to isolate cannabinoids and concentrate them into a potent extract. Hopefully, we’ll be seeing CBG dabs and oils in the future. Seeing that CBD’s popularity has skyrocketed in recent years, even in the recreational market, we’re curious to see how far CBG will go.


This cannabinoid behaves very interestingly. It seems to synergise with other chemical compounds in cannabis, much like how CBD and THC are proposed to work together. CBG is an agonist to the CB1 receptor and as such, affects the central nervous system. This is understood to help reduce the THC-induced paranoia that cannabis can provide. Although CBG interacts with CB1 receptors in a much weaker way than THC, it does sustain observable effects.

It is also known that CBG interacts with the CB2 receptor. However, it’s not fully understood how this occurs, and to what end. What is known is that it inhibits the uptake of the chemical GABA. Very much like CBD, this also adds to decreased anxiety, paranoia, and depression.


Although they’re both non-psychoactive compounds in cannabis, there are a few factors that differentiate CBG from CBD. One of the most evident differences is that CBD does not directly interact with CB1 or CB2 receptors. These are the two predominant cannabinoid receptors in our brain and central nervous system. CBG, on the other hand, will act on the receptors as a partial agonist. But these effects are nowhere near as powerful as THC.

CBG will also increase the production of anandamide, our body’s main endogenous cannabinoid or “endocannabinoid”. Anandamide helps regulate sleep, appetite, and memory by also acting on CB1 and CB2 receptors. CBD, on the other hand, reduces anandamide’s access to fatty acids that act as a transport molecule. This means that it slows down the molecule’s process of entering the system.

We still know much more about THC and CBD than this relatively new cannabinoid. But its potential is already becoming a reality. The only problem is that most studies haven’t reached the clinical stage yet. Only future research will be able to confidently conclude more about the benefits of CBG.

We’ve all read that cannabis has become a real treatment option for certain symptoms of specific types of cancer. In a 2009 study, researchers concluded that CBG may play an integral role in this form of treatment; not only for its potential applications as a pain-reliever, but to slow tumour growth as well. It’s not the only cannabinoid involved in this, but it appears to be a valid component.

CBG may also contribute heavily to the treatment of glaucoma. This comes as no surprise. At one point, this condition was the oldest trick in the book to get a medical cannabis card. Before 1990, researchers thought THC was the only substance responsible for this; later, it was concluded that CBG is also extremely important in combating glaucoma.

Cannabis has also recently challenged stigma by showing that it works as a neuroprotective agent. This means that it functions to prevent age-related conditions and nerve cell degeneration in the brain. In 2015, a study looked into CBG and this effect on mice with Huntington’s disease. The study confirmed CBG’s neuroprotective capabilities.

A 2017 research paper showed how a purified form of CBG did wonders as an appetite stimulant in rats. This might become a powerful complement for other conventional treatments that have appetite-loss as a side effect. The future looks bright for this cannabinoid and consequently, for the cannabis community as a whole. Now that you’re more informed on CBG and what it can achieve, it’s up to you to help spread the word.


As we’ve covered, CBG-rich strains are hard to come by. Research hasn’t gone much into it because the demand is very low. But with the expansion of the cannabis market, more and more people are looking for ways that cannabis can help them.

For now, the team at Zamnesia offers a few strains with noticeable CBG contents. These aren’t CBG-dominant strains, as that is not a reality at present. However, the following three varieties are noted for their above-average CBG concentrations.


Let’s first look into Destroyer. This great mix between Meao Thailand and a Mexican/Columbian hybrid creates a rare strain that’s amongst the very few pure sativas to survive in the world. With a THC percentage as high as 20%, this strain will surely satisfy the experienced stoner. Although strong, it’s a clear head high that’s paired with some refreshing and sweet floral/lavender aromas. The exact CBG percentage is not known, but is said to be relatively high.

Next, we have Exodus Cheese. This indica-dominant beauty with 0.26% CBG will be another great place to start for those interested in experimenting with CBG-rich strains. This one has 2% less THC than Destroyer above, making the CBG more noticeable. With its trichome-covered buds, Exodus Cheese delivers a solid high with very earthy and woody flavours. The effects aren’t immediate, but they will surely please you when you feel your body overwhelmed by dankness.

And finally, we had to bring you Williams Wonder by Sickmeds Seeds. With 0.86% CBG, this will probably be the most noticeable CBG-rich strain. Not that you’ll feel the CBG with over 20% THC, but it will be a great high for sure. Being 100% indica, get ready for super mellow and chill effects. This is also a great choice if you’re looking to tackle depression, anxiety, pain, nausea, and even insomnia. It’s an overall indica masterpiece.

CBG (cannabigerol) is the original cannabinoid. Studies on this non-psychoactive compound have shown it to be potentially beneficial for several applications. MediHemp organic 5% CBG oil begins its life in MediHemp’s own certified organic hemp farms in beautiful Austria. A chemical-free life from farm to you ensures only the purest products make their way into your body. Cold-pressed seed and whole plant extracts are combined to produce this vital oil. MediHemp 5% CBG oil is rich in amino acids and essential fatty acids with phenols, vitamins, and minerals. Feel the powerful difference with twenty drops a day.

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